1. lékařská fakulta Univerzita Karlova 1. lékařská fakulta Univerzita Karlova UNCE 204021 - UNCE/MED/016
lvysa 04.04.2018

Anna Jonášová: Lenalidomide treatment in lower risk myelodysplastic syndromes

Lenalidomide treatment in lower risk myelodysplastic syndromes—The experience of a Czech hematology center. (Positive effect of erythropoietin±prednisone addition to lenalidomide in refractory or relapsed patients). Jonasova A, Neuwirtova R, Polackova H, Siskova M, Stopka T, Cmunt E, Belickova M, Moudra A, Minarik L, Fuchs O, Michalova K, Zemanova Z. Leukemia Research 69 (2018) 12-17. 2018 March 27. https://doi.org/10.1016/j.leukres.2018.03.015 . [PDF] (IF 2.501)

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tstopka 03.04.2018

Kamila Polgárová: Somatic mutation dynamics in MDS patients

Somatic mutation dynamics in MDS patients treated with azacitidine indicate clonal selection in patients-responders. Polgarova K, Vargova K, Kulvait V, Dusilkova N, Minarik L, Zemanova Z, Pesta M, Jonasova A and Stopka T. Oncotarget. 2017 Dec 6. [PDF] (IF 5.168)

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tstopka 21.12.2017

Nina Dusílková & Petra Bašová: Plasma microRNAs in Cutaneous Lymphoma, in press IJMS

 Plasma miR-155, miR-203, and miR-205 are Biomarkers for Monitoring of Primary Cutaneous T-cell Lymphomas. Dusilkova N, Basova P, Polivka J, Kodet O, Kulvait V, Pesta M, Trneny M, Stopka T. Int J Mol Sci. 2017 Oct 15;18(10). pii: E2136. doi: 10.3390/ijms18102136. [PDF] (IF: 3.226)

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tstopka 21.12.2017

Petra Bašová: Serum microRNAs in Breast Cancer Relapse prediction, in press in IJMS

Plasma miR-155, miR-203, and miR-205 are Biomarkers for Monitoring of Primary Cutaneous T-cell Lymphomas. Basova P, Pesta M, Sochor M, Stopka T. Int J Mol Sci. 2017 Oct 10;18(10). pii: E2116. doi: 10.3390/ijms18102116. [PDF] (IF 3.226)

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lvysa 21.12.2017

Pavel Klener: Hematopoiesis in patients with mature B-cell malignancies in Heamatologica

Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement. Maswabi BC, Molinsky J, Savvulidi F, Zikmund T, Prukova D, Tuskova D, Klanova M, Vockova P, Lateckova L, Sefc L, Zivny J, Trneny M, Klener P.  Haematologica. 2017 Apr;102(4):e152-e155. doi: 10.3324/haematol.2016.151571. [PubMed] (IF 7.702)

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tstopka 26.10.2017

Juraj Kokavec: mouse model of Smarca5 in HSCs

The ISWI ATPase Smarca (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells. Kokavec J, Zikmund T, Savvulidi F, Kulvait V, Edelmann W, Skoultchi AI, Stopka T. Stem Cells. 2017 Mar 9. doi: 10.1002/stem.2604. [PubMed] (5-year IF 6.872)

Výsledek obrázku pro Stem Cells Journal logo


tstopka 11.10.2017

Karina Vargová - MS on miR-155/miR-150 network in CLL now in press in BCJ

MiR-155/miR-150 network regulates progression through the disease phases of chronic lymphocytic leukemia.Vargova K, Pesta M, Obrtlikova P, Dusilkova N, Minarik L, Vargova J, Berkova A, Zemanova Z, Michalova K, Spacek M, Trneny M, Stopka T. Blood Cancer J. 2017 Jul 21;7(7):e585. doi: 10.1038/bcj.2017.63. [PDF] (IF 6.126)


 

lvysa 26.10.2017

Pavel Klener: Mantle cell lymphoma-variant Richter syndrome in IJC

Mantle cell lymphoma-variant Richter syndrome: Detailed molecular-cytogenetic and backtracking analysis reveals slow evolution of a pre-MCL clone in parallel with CLL over several years. Klener P, Fronkova E, Berkova A, Jaksa R, Lhotska H, Forsterova K, Soukup J, Kulvait V, Vargova J, Fiser K, Prukova D, Alam M, Calvin Lenyeletse Maswabi B, Michalova K, Zemanova Z, Jancuskova T, Pekova S, Trneny M.  Int J Cancer. 2016 Nov 15;139(10):2252-60. doi: 10.1002/ijc.30263. [PubMed] (IF 6.513)

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tstopka 11.10.2017

Jarmila Vargová: MARCKS - nový terapeutický cíl pro Lymfom z plášťové zóny

Differential Expression, Localization and Activity of MARCKS between Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia. Vargova J, Vargova K, Dusilkova N, Kulvait V, Pospisil V, Zavadil J, Trneny M, Klener P, Stopka T. Blood Cancer J. 2016 Sep 23;6(9):e475. doi: 10.1038/bcj.2016.80. [PDF] (IF 4.411)


lvysa 26.10.2017

Pavel Klener: Role of BCL2, MCL1 and BCL-XL in the survival of DLBCL in CCR

Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma. Klanova M, Andera L, Brazina J, Svadlenka J, Benesova S, Soukup J, Prukova D, Vejmelkova D, Jaksa R, Helman K, Vockova P, Lateckova L, Molinsky J, Maswabi BC, Alam M, Kodet R, Pytlik R, Trneny M, Klener P.  Clin Cancer Res. 2016 Mar 1;22(5):1138-49. doi: 10.1158/1078-0432.CCR-15-1191. [PubMed] (IF 9.619)

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tstopka 26.10.2017

Příspěvek Mgr. J. Kokavce v časopise Development

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A.  2016 Jun 1;143(11):1937-47. doi: 10.1242/dev.135285. [PDF] (IF 6.462)

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tstopka 03.04.2018

Publikace Dr. Pavla Burdy v PloS One a BBA

GATA-1 inhibits PU.1 gene via DNA and histone H3K9 Methylation of its Distal Enhancer in Erythroleukemia. Burda P, Vargova J, Curik N, Salek C, Papadopoulos GL, Strouboulis J, Stopka T. PLoS One, 2016 Mar 24;11(3):e0152234 [PDF] (IF 3.234)



Distinct and overlapping DNMT1 interactions with multiple transcription factors in erythroid cells: evidence for co-repressor functions. Papageorgiou DN, Karkoulia E, Amaral-Psarris A, Burda P, Kolodziej K, Demmers J, Bungert J, Stopka T, Strouboulis J. Biochim Biophys Acta. 2016 Dec;1859(12):1515-1526. doi: 10.1016/j.bbagrm.2016.09.007. [PDF] (IF: 5.373)